Distribution and Incidence Ratesa of Primary Brain and Central Nervous System Tumors by Histology Adjusted to the 1970 and 2000 U.S. Standard Populations,
CBTRUS 1992-1997b
| HISTOLOGY |
Total Number |
% of All Reported Brain Tumors |
Mean Age at Diagnosis |
Adjusted Rate (S.E.) |
| 1970 US |
2000 US |
| Tumors
of neuroepithelial tissue |
|
Diffuse astrocytoma
(protoplasmic, fibrillary)
|
409 |
1.1 |
47 |
0.12 (0.01) |
0.13 (0.01) |
Anaplastic astrocytoma
|
1515 |
3.9 |
50 |
0.44 (0.01) |
0.49 (0.01) |
Glioblastoma
|
8,967 |
23.1 |
62 |
2.60 (0.03) |
2.96 (0.03) |
Pilocytic astrocytoma
|
719 |
1.9 |
17 |
0.28 (0.01) |
0.23 (0.01) |
Unique astrocytoma
variants
|
159 |
0.4 |
37 |
0.05 (0.00) |
0.05 (0.00) |
Oligodendroglioma
|
1,053 |
2.7 |
42 |
0.30 (0.01) |
0.34 (0.01) |
Anaplastic
Oligodendroglioma
|
315 |
0.8 |
46 |
0.09 (0.01) |
0.10 (0.01) |
Ependymoma/anaplastic
ependymoma
|
728 |
1.9 |
35 |
0.23 (0.01) |
0.23 (0.01) |
Ependymoma variants
|
125 |
0.3 |
39 |
0.04 (0.00) |
0.04 (0.00) |
Mixed glioma
|
393 |
1.0 |
40 |
0.11 (0.01) |
0.12 (0.01) |
Astrocytoma, NOS
|
2,364 |
6.1 |
47 |
0.70 (0.01) |
0.76 (0.02) |
Glioma malignant, NOS
|
1,086 |
2.8 |
47 |
0.33 (0.01) |
0.35 (0.01) |
Choroid plexus
|
96 |
0.2 |
27 |
0.03 (0.00) |
0.03 (0.00) |
Neuroepithelial
|
54 |
0.1 |
43 |
0.02 (0.00) |
0.02 (0.00) |
Benign and malignant neuronal/glial,
neuronal and mixed
|
371 |
1.0 |
26 |
0.13 (0.01) |
0.12 (0.01) |
Pineal parenchymal
|
66 |
.02 |
30 |
0.02 (0.00) |
0.02 (0.00) |
Embryonal/primitive/medulloblastoma
|
757 |
1.9 |
16 |
0.28 (0.01) |
0.24 (0.01) |
| Tumors
of cranial and spinal nerves |
|
Nerve sheath, benign
and malignant
|
2,667 |
6.9 |
52 |
0.78 (0.02) |
0.88 (0.02) |
Other tumors of cranial and spinal nerves
|
2 |
0.0 |
42 |
0.00 (0.00) |
0.00 (0.00) |
| Tumors
of the meninges |
|
Meningioma
|
10,001 |
25.7 |
62 |
2.75 (0.03) |
3.31 (0.03) |
Other mesenchymal,
benign and malignant
|
142 |
0.4 |
47 |
0.04 (0.00) |
0.05 (0.00) |
Hemangioblastoma
|
293 |
0.8 |
46 |
0.09 (0.01) |
0.10 (0.01) |
| Lymphomas
and hemopoietic neoplasms |
|
Lymphoma
|
1,174 |
3.0 |
54 |
0.32 (0.01) |
0.38 (0.01) |
| Germ
Cell Tumors and Cysts |
|
Germ cell tumors, cysts and heterotopias
|
224 |
0.6 |
18 |
0.09 (0.01) |
0.07 (0.00) |
| Tumors
of the sellar region |
|
Pituitary
|
2,399 |
6.2 |
49 |
0.69 (0.01) |
0.79 (0.02) |
Craniopharyngioma
|
282 |
0.7 |
35 |
0.09 (0.01) |
0.09 (0.01) |
| Local
extensions from regional tumors |
|
Chordoma/chodrosarcoma
|
78 |
0.2 |
55 |
0.02 (0.00) |
0.03 (0.00) |
| Unclassified
tumors |
|
Hemangioma
|
120 |
0.3 |
41 |
0.04 (0.00) |
0.04 (0.00) |
Neoplasm, unspecified
|
2,270 |
5.8 |
63 |
0.61 (0.01) |
0.75 (0.02) |
All Other
|
19 |
0.0 |
47 |
0.01 (0.00) |
0.01 (0.00) |
| TOTAL |
38,848 |
100.0 |
54 |
11.32 (0.06) |
12.73 (0.06) |
a Rates are per 100,000 person-years.
b Includes data from 11 of the 14 regions listed in Table 2; Maine, New Mexico and Virginia are excluded.
Abbreviations used: CBTRUS, Central Brain Tumor Registry of the United States; NOS, not otherwise specified.
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